الگو:PBB/10014

Histone deacetylase 5
شاخص‌ها
نماد ژن	HDAC5; HD5; NY-CO-9
شناسه‌های بیرونی	OMIM: 605315 MGI: 1333784 HomoloGene: 3995 ChEMBL: 2563 GeneCards: HDAC5 Gene
EC number	3.5.1.98
هستی‌شناسی ژن Molecular function • transcription corepressor activity • histone deacetylase activity • protein kinase C binding • protein binding • transcription factor binding • NAD-dependent histone deacetylase activity (H3-K14 specific) • transcription regulatory region DNA binding • metal ion binding • NAD-dependent histone deacetylase activity (H3-K9 specific) • NAD-dependent histone deacetylase activity (H4-K16 specific) • repressing transcription factor binding • NAD-dependent histone deacetylase activity (H3-K18 specific) Cellular component • histone deacetylase complex • nucleus • nucleolus • cytoplasm • Golgi apparatus • cytosol • nuclear body Biological process • negative regulation of transcription from RNA polymerase II promoter • osteoblast development • chromatin organization • chromatin remodeling • chromatin silencing • transcription, DNA-dependent • inflammatory response • Notch signaling pathway • heart development • regulation of myotube differentiation • negative regulation of myotube differentiation • chromatin modification • histone deacetylation • B cell differentiation • cellular response to insulin stimulus • B cell activation • response to cocaine • regulation of protein binding • negative regulation of osteoblast differentiation • negative regulation of transcription, DNA-dependent • positive regulation of transcription from RNA polymerase II promoter • positive regulation of sequence-specific DNA binding transcription factor activity • negative regulation of cell migration involved in sprouting angiogenesis Sources: Amigo / QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونه‌ها	انسان	موش
آنتره	10014	15184
آنسامبل	ENSG00000108840	ENSMUSG00000008855
UniProt	Q9UQL6	A2AWS5
RefSeq (mRNA)	NM_001015053.1	NM_001077696.1
RefSeq (protein)	NP_001015053.1	NP_001071164.1
موقعیت (UCSC)	Chr 17: 42.15 – 42.2 Mb	Chr 11: 102.19 – 102.23 Mb
جستجوی پاب‌مد	[۱]	[۲]